Publicaciones

1.         Asthma mortality, inhaled steroids, and changing asthma therapy in Argentina (1990-1999). Neffen H, Baena-Cagnani C, Passalacqua G, Canonica GW, Rocco D. Respir Med.  2006;100(8):1431-5.

2.         Not well controlled asthma is associated with increased use of unscheduled healthcare: Analysis in 26 countries. Lai CK, Neffen H, Vervloet D, Williams AE, Lloyd AC. Prim Care Respir J. May 2006.04.134.

3.         Recomendaciones para el diagnóstico y tratamiento del asma de difícil control (ADC). D. Colodenco, H. Neffen, C. Baena Cagnani, R. Rojas, C. D. Crisci.  Archivos Alergia e Inmunología Clínica Vol 37, Suplemento 1. 2006.

4.         Consenso Latinoamericano sobre el asma de difícil control.  Neffen Hugo, Tálamo Carrillo Carlos,  Barillas Rodríguez Juan Manuel, et al. Drugs of Today 2006, Vol. 42, Supl. III/MX. 2006.

5.         Asthma Prevalence and Risk Factors in Latin America. Neffen, H. Current Allergy & Clinical Immunology, Vol 20, Nº.1, p. 8-10. March 2007.

6.         Reliability and factor analysis of the Spanish version of the Asthma Control Test. Gustavo J. Rodrigo; José Pedro Arcos, Luis J. Nannini, Hugo Neffen; Marisa González Broin, Mariela Contrera and Luis Piñeyro. Annals of Allergy, Asthma and Immunology. Volume 100, January 2008.

7.         Consenso Latinoamericano sobre el asma de difícil control. Actualización 2008.  Neffen, Hugo; Tálamo Carrillo, Carlos; Colodenco, Daniel, et al. Drugs of Today, 2008, Vol. 44, Supl. 3. 2008.

8.         Impacto del tratamiento preventivo con Agonistas 2 Adrenérgicos de Acción Larga y Glucocorticoides Inhalados en la morbimortalidad de 1.543 episodios de exacerbación grave de asma. V Plaza, J Bellido-Casado, GJ Rodrigo, C Torres, G Rodríguez-Trigo, R Sepúlveda, H. Neffen y M Perpiñá. Archivos de Bronconeumología. (SEPAR-ALAT), 2009; 45:545-9.

9.         Relationship between the characteristics of hospitalized acute asthma patients and the severity of their asthma. A case-control study. Gustavo J. Rodrigo, Vicente Plaza, Hugo E. Neffen, Gur Levy, Miguel Perpiñá Tordera. Allergologia et Immunopathologia, 2009; 37(5):225-229.

10.       The impact of preventive treatment with long-acting b2 adrenergics agonist and inhaled glucocorticoids in the morbility and mortality of 1.543 events of severe exacerbations of asthma. Bellido-Casado J, Plaza V, Rodrigo G, Torres C, Rodriguez-Trigo G, Sepulveda R, Neffen H, Perpiña M.  ERS Congress. Vienna, September 13, 2009

11.       Characteristics of patients hospitalized for acute severe asthma over a ten year period (1994-2004) in Spain and Latin-america: the eagle study. Gustavo J. Rodrigo, Jesús Bellido-Casado, Hugo Neffen, María Teresa Bazús, Gur Levy, Joseph Armengol. Brazilian Journal of Pneumology, 2009; 35(7):635-644.

12.       Rinitis alérgica en Latinoamérica. Manejo actual y estrategias para la adopción de guías de diagnóstico y tratamiento. H. Neffen, D. Solé, J. Máspero y colaboradores. Drugs of Today 2009, 45 (Supl. 4): 1-19.

13.       Formoterol for acute asthma in the Emergency Department: a systematic review with meta-analysis. Gustavo J. Rodrigo, Hugo E. Neffen,  Federico Daniel Colodenco, José A. Castro-Rodriguez. Ann Allergy Asthma Immunol. 2010;104:247–252

14.       Nasal allergies in the Latin American population: Results from the Allergies in Latin America survey - Hugo Neffen, M.D. Joao F. Mello, Jr., M.D., Dirceu Sole, M.D., Charles K. Naspitz, M.D., Alberto Eduardo Dodero, M.D., Héctor León Garza, M.D., Edgard Novelo Guerra, D., Carlos Baez-Loyola, M.D., John M. Boyle, Ph.D., and Mark A. Wingertzahn, Ph.D. Allergy and Asthma Proceedings - May–June 2010, Vol. 31, No. 3 (Suppl 1):9-27.

15.       How can we improve the management of allergic rhinitis in Latin America? Neffen, H - Allergy Asthma Proc. 2010 Jun 16.

16.       Ciclesonide, a hypotonic intranasal corticosteroid - Hugo Neffen, M.D., and Mark A. Wingertzahn, Ph.D. - May–June 2010, Vol. 31, No. 3 (Suppl 1).

17.       Efficacy and safety of subcutaneous omalizumab versus placebo as add on therapy to corticosteroids for children and adults with asthma: a systematic review – Rodrigo, G. Neffen H, Castro-Rodriguez, J. - CHEST / 139 / 1 / JANUARY, 2011

18.       Guía ALERTA 2. América Latina y España: Recomendaciones para la prevención y el Tratamiento de la exacerbación Asmática - Gustavo J. Rodrigo, Vicente Plaza Moral, Santiago Bardagí Forns, José A. Castro-Rodríguez, Alfredo de Diego Damiá, Santos Liñán Cortés, Carlos Melero Moreno, Luis J. Nannini, Hugo Neffen y Jorge Salas et al / Arch Bronconeumol. 2010;46(Supl 7):2-20

19.       Efficacy of fluticasone furoate nasal spray vs. placebo for the treatment of ocular and nasal symptoms of allergic rhinitis: a systematic review. - Rodrigo GJ, Neffen, H, Clin Exp Allergy. 2010 ;41(2):160-70.

20.       The Burden of Unscheduled Health Care for Asthma in Latin America - H Neffen, SN Gonzalez, CC Fritscher, C Dovali, AE Williams - J Investig Allergol Clin Immunol 2010; Vol. 20(7): 596-601
21.       Allergen immunotherapy for prevention and treatment of respiratory allergy in childhood.  Saranz RJ, Lozano A, Cáceres ME,… Neffen H, et al. Arch Argent Pediatr 2010;108(3):258-65. doi: 10.1590/S0325-00752010000300020.

22.       Asthma programmes in diverse regions of the World: challenges, successes and lessons learnt – U. G. Lalloo, R. D. Walters, M. Adachi, T. De Guia, A. Emelyanov, C. C. Fritscher, J. Hong, C. Jimenez, G. G. King, J. Lin, A. Loaiza, G. Nadeau, H. Neffen, B. E. Sekerel, A. Yorgancioglu, H. J. Zar.Int J Tuberc Lung Dis. 2011 Dec;15(12):1574-87

23.       Comparison of Indacaterol with Tiotropium or twice-daily long-acting Beta-agonists for stable copd: a systematic review  - G. Rodrigo, H. Neffen - Chest. 2012 Nov;142(5):1104-1110. doi: 10.1378/chest.11-2252.

24.       Knowledge and Management of Anaphylaxis in Primary Care Settings in Argentina. L. R. F. Ardusso, M. Carignani, L. Sanchez, J. L. Molinas, M. Ardusso, M. Gonzalez Broin, H. Neffen. JACI 2012;29(2): AB178 (#673).

25.       Treatment of Nasal Allergies: Results from the Allergies Surveys in America, Asia Pacific, Latin America, and Middle East. Michael S. Blaiss · Connie Katelaris · Hugo E. Neffen. World Allergy Organization Journal 02/2012; 5(Suppl 2):S146-S146.

26.       The Impact of Nasal Allergies. Michael S. Blaiss · Connie Katelaris · Hugo E. Neffen. World Allergy Organization Journal 02/2012; 5(Suppl 2):S192-S192.

27.       Asma de difícil control en niños y adolescentes: estrategias diagnóstico-terapéuticas:   H. Neffen, S. Vidaurreta, A. Balanzat, M. De Gennaro, V. Giubergia,  J. Maspero, R. Saranz, A. Teper – Revista Medicina (Buenos Aires) 2012; 72: 403-413.

28.       Asma de difícil control en niños y adolescentes. Estrategias diagnóstico-terapéuticas. Neffen HE, Vidaurreta S, Balanzat A, et al. Medicina (Buenos Aires), 72(5), 403-413. http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0025-76802012000600010&lng=es&tlng=pt.

29.       Consenso SEPAR-ALAT sobre terapia inhalada. Archivos de Bronconeumología. 2013. Volumen 49 - Extraordinario 1

30.       Asthma admissions: Characteristics of patients admitted to a specialized respiratory hospital. Fabián Caro, Santiago Auteri, Daniel Colodenco, Ricardo Del Olmo, Glenda Ernst, Martín Fernández, Guillermo Menga, José Luis Morero, Eduardo Schiavi, Hugo Neffen, Santiago Rossi. European Respiratory Journal. Volume 42 / Supplement 57 / September 2013. 424s.

31.       Inequities and Asthma. Neffen Hugo. Global Atlas of Asthma. EAACI 2013: 120-121

32.       Levels of IL-8 and IL17-A in Sputum Samples From Severe Asthma Patients. Chest 10/2013; 144 (4_MeetingAbstracts):82A.

33.       Prevalencia, impacto y manejo de la rinitis alérgica en Latinoamérica. Revista de Rinología, Barcelona, España. Revista de Rinología, 2014;14(1):19-28.

34.       Significant Increase of IL-8 Sputum Levels in Treatment Resistant Severe Asthma Compared with Difficult to Treat Severe Asthma Patients. J Genet Syndr Gene Ther 2014, http://dx.doi.org/10.4172/2157-7412.1000218  

35.       Guía argentina de urticaria y angioedema. Revista Medicina. (Buenos Aires) Vol. 74 Supl. I – 2014.

36.       A systematic review on the efficacy and safety of a fixed-dose combination of Umeclidinium and Vilanterol for the treatment of COPD. Chest on line 2015.

37.       Systematic review on the use of omalizumab for the treatment of asthmatic children and adolescents. Rodrigo GJ, Neffen H. Pediatr Allergy Immunol. 2015 May 11. doi: 10.1111/pai.12405. [Epub ahead of print]

38.       "Allergen Immunotherapy on the Way to Product-based Evaluation. A WAO Statement"
Authors: Claus Bachert; Mark Larche; Sergio Bonini; G Walter Canonica; Thomas Kuendig; Desiree Larenas-Linnemann; Dennis K Ledford; Hugo Neffen; Ruby Pawankar; Giovanni Passalacqua. World Allergy Organization Journal 2015, 8 :29 (16 September 2015)

39.       Assessment of Acute Asthma severity in the ED: Are heart and respiratory rates relevant? The American Journal of Emergency Medicine. 33 (2015) 1583-1586. Rodrigo GJ, Neffen, H.

40.       MACVIA – ARIA Sentinel Network for allergic rhinitis (MASK – rhinitis): The new generation guideline implementation. J Bousquet J, HJ Schunemann, J Fonseca et al. Allergy – July 2015.

41.       A 121/2-year journey of a patient with Samter triad syndrome and sporadic omalizumab use. Ardusso L.R.F.; Neffen, H.  Annals of Allergy, Asthma & Immunology. 115 (2015) 451-457.

42.       Gobal Atlas of Allergic Rhinitis and Chronic Rhinosinusitis. Treatment of Allergic Rhinitis – Nasal Steroids 2015:95-96.

43.       Prevalence And Features Of Asthma. Results Of A Population-Based Nationwide Survey In Argentina. A. J. Videla , S. Arias , J. C. Bossio , C. A. Calabrese , G. Armando , H. Neffen. Am J Respir Crit Care Med 193;2016:A2945.

44.       Asthma-COPD Overlap Syndrome (ACOS): A Controversial Concept. Gustavo J. Rodrigo, Hugo Neffen, Vicente Plaza. Current Opinion in Allergy and Clinical Immunology: February 2017 - Volume 17 - Issue 1 - p 36–41 doi: 10.1097/ACI.0000000000000326.

45.       A Systematic Review with Meta-Analysis of Fluticasone Furoate/Vilanterol Combination for the Treatment of Stable COPD. Gustavo J. Rodrigo, Hugo Neffen. Journal: Pulmonary Pharmacology & Therapeutics. 42 (2017) 1 – 6.

46.       Uncontrolled Asthma in Specialized Centers in Latin America: Findings from the Asthma Control in Latin America (ASLA) Study. Hugo E. Neffen, Edith Vallejo-Perez, Marco Chahuan, et. al. AB206 - J Allergy Clin Immunol. February 2017.

47.       Efficacy and Safety of Tiotropium in School-age Children with Moderate to Severe Symptomatic Asthma: Results from a Systematic Review with Meta-Analysis. Gustavo Rodrigo, Hugo Neffen Pediatr Allergy Immunol. 2017; Sep;28(6):573-578. doi: 10.1111/pai.12759.

48.       ARIA 2016 executive summary: Integrated care pathways for predictive medicine throughout the life cycle in Argentina Resumen ejecutivo de ARIA 2016: vías integradas de atención para la medicina predictiva a lo largo del ciclo de vida en Argentina. Juan Carlos Ivancevich, Hugo Neffen, et al. Rev Alerg Mex. 2017;64(3):298-308.

49.       CHRODIS criteria applied to the MASK (MACVIA‑ARIA Sentinel NetworK) Good Practice in allergic rhinitis: a SUNFRAIL report. Bousquet J, Onorato GL, Bachert C, … Neffen H, et al. Clin Transl Allergy 2017;7:37. DOI 10.1186/s13601-017-0173-8

50.       Prevalencia y características clínicas del asma en adultos jóvenes en zonas urbanas de Argentina. Prevalence and features of asthma in young adults in urban areas of Argentina."(Ref. ARBR-D-17-00277R1).  Arias, Sergio; Neffen Hugo, et al. Arch Bronconeumol. 2018;54(3):134–139

51.       ARIA 2017: a Review of Major Changes and Innovations. Neffen Hugo, Ivancevich Juan Carlos. Curr Treat Options Allergy June 2018, Volume 5, Issue 2, pp 266–273. https://doi.org/10.1007/s40521-018-0166-4

52.       MASK 2017: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma multimorbidity using real-world-evidence. Bousquet et al. Clin Transl Allergy (2018) 8:45 https://doi.org/10.1186/s13601-018-0227-6

53.       The Global Asthma Report 2018: Improving Asthma Management at the Primary Healthcare Level. Hugo Neffen, Alvaro Teijeiro. Global Asthma Network 2018:55.

54.       Key factors associated with uncontrolled asthma – the Asthma Control in Latin America Study. Hugo Neffen, Marco Chahuàn, Dante D. Hernández, et al. Journal of Asthma, DOI: 10.1080/02770903.2018.1553050.

55.       Intervención ambiental en las enfermedades respiratorias. Ardusso LR, Neffen HR, Fernandez Caldas E, et al. Medicina (Buenos Aires), 79(2), 123-136. http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0025-76802019000300007&lng=es&tlng=es.

56.       Transfer of innovation on allergic rhinitis and asthma multimorbidity in the elderly (MACVIA-ARIA) - EIP on AHA Twinning Reference Site (GARD research demonstration project). Bousquet J,  Agache I, Aliberti MR, … Neffen H, et al. Allergy 2018;73(1):77-92. https://doi.org/10.1111/all.13218.

57.       Asthma severity in four countries of Latin America. Hugo Neffen, Felipe Moraes, Karynna Vianna, et al.  BMC Pulmonary Medicine (2019) 19:123. https://doi.org/10.1186/s12890-019-0871-1

58.       MASK (Mobile Airways Sentinel Network), a mobile App with ARIA’s comprehensive solution in Spanish-speaking countries. Désirée Larenas-Linnemann,1 Joaquim Mullol,2 Juan Carlos Ivancevich, et al. Rev Alerg Mex. 2019;66(2):263-268.

59.       The MASK Study Group (2019). Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma. Bousquet, J., Bedbrook, A., … Neffen H, et al. Clinical and Translational Allergy, 9(1), [16]. https://doi.org/10.1186/s13601-019-0252-0

60.       The Explosion of OTC Management of Allergic Rhinitis: Costs and Risks Juan Carlos Ivancevich, Hugo Neffen, Jorge Fernando Máspero. Curr Treat Options Allergy. DOI 10.1007/s40521-019-00222-1

61.       Executive Summary of ARIA 2019: Integrated care pathways for allergic rhinitis in Argentina, Spain and Mexico. Ivancevich JC, Cardona V, Larenas Linnemann D … Neffen H, et al. Rev Alerg Mex 2019;66(4):409-425.

62.       Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence. Bousquet J, Schünemann HJ, Togias A, …. Neffen H, et al. Journa of Allergy and Clinical Immunology. Volume 145, Issue 1, January 2020, Pages 70-80.e3

63.       ARIA-EAACI statement on asthma and COVID-19 (June 2, 2020). Bousquet J, Jutel M, Akdis CA, …. Neffen H, et al. First published: 26 June 2020 https://doi.org/10.1111/all.14471

64.       Global Atlas of Asthma. Inequities and Asthma. Hugo Neffen, Alvaro Cruz, Jorge Máspero. 2021: 217-219.

65.       Management of anaphylaxis due to COVID-19 vaccines in the elderly. Bousquet J, Agache I, Blain H, …., Neffen H, et al. Allergy Volume76, 2021(10); 2952-2964 https://doi.org/10.1111/all.14838
66.       ARIA-EAACI care pathways for allergen immunotherapy in respiratory allergy. Bousquet J, Pfaar O, Agache I, … Neffen H, et al. CTA 2021 https://doi.org/10.1002/clt2.12014

67.       Differentiation of COVID-19 signs and symptoms from allergic rhinitis and common cold: An ARIA-EAACI-GA2LEN consensus. Jan Hagemann, Garbrielle Onorato, Marek Jutel, et al. Allergy 2021:00:1-13 doi:10.1111/all:14815.

68.       Consensus on mild asthma management: results of a modified Delphi study. Christian Domingo, Gabriel Garcia, Bilun Gemicioglu, Giap Vu Van, Désirée Larenas-Linnemann, Hugo Neffen, et al. https://doi.org/10.1080/02770903.2022.2034850

69.       USO Y ABUSO DE CORTICOIDES SISTÉMICOS EN LA ARGENTINA: UN LLAMADO A LA ACCIÓN. Jorge Máspero, Hugo Neffen, Pascual Valdez, et al. Rev Arg Med 2022;10(1):19-25.

70.       Real-world data using mHealth apps in rhinitis, rhinosinusitis and their multimorbidities.  Sousa-Pinto B, Anto A, Berger M, … Neffen H, et al. Clinical and Translational Allergy 2022;12(11): . https://doi.org/10.1002/clt2.12208.

71.       Development and validation of an electronic daily control score for asthma (e-DASTHMA): a real-world direct patient study. Sousa-Pinto B, Jácome C, Margarida Pereira A, …., Neffen H, et al. Lancet Digit Health 2023;5: e227–38.

72.       RHINITIS ASSOCIATED WITH ASTHMA IS DISTINCT FROM RHINITIS ALONE: THE ARIA-MEDALL HYPOTHESIS J Bousquet, E Melén, T Haahtela, et al.– Allergy 2023. doi: 10.1111/all.15679